Professor Oloke was born in 17th December 1958. He obtained a PhD in Microbiology from Obafemi Awolowo University in 1989. He became a Professor of Microbiology and Biotechnology at Ladoke Akintola University of Technology in 1999. 

Between 1993 and 1994 he did some genetic engineering work on an unusual isolate of Bacillus thurigiensis at the Biology Department University of Waterloo; Ontario Canada. As a result of this preliminary work, the organism was deposited at the American Culture Collection Centre (NRRL) as Bacillus thurigiensis oloke and filed for American Patent with ascension number WO/1997/041235.  

The research group of Professor Oloke successfully constructed a Computerized Bioreactor and Computerized Temporary Immersion Bioreactor which are very vital in microbial fermentation and plant tissue culture. The Bioreactors were adjudged one of the ten outstanding research work at the First ever NUC Research Fair in Abuja. This feat contributed to fetching Ladoke Akintola University of Technology the First position among all the States Universities of Nigeria for three consecutive years. This research discovery has since been acquired by the National Biotechnology Development Agency; Abuja; Nigeria.

In a quest to find a long-lasting solution to immuno-compromised conditions, Professor Oloke formulated an immune modulating agent known as Trinity Immuno-booster (Trino IB).  It was given a NAFDAC number in 2007 and has been successfully used for the management of different immuno-compromised conditions both in Nigeria and some other countries. As a result of this feat Professor Oloke was conferred with National Productivity Order of Merit Award by the Federal Government of Nigeria in August 2012.

In Ladoke Akintola University of Technology, Ogbomoso; he has served in different Administrative Posts like Head, Department of Pure and Applied Biology; Director, Academic Planning and Chairman, Pre-Degree Science Program. 

Professor Oloke has served as a member of Governing Councils for Ladoke Akintola University of Technology and at The Nigerian Baptist Theology Seminary, Ogbomoso, Nigeria   

He has graduated more than twenty Doctoral students some of which have become Professors.

Professor Oloke who has served as a member of NUC Accreditation Panels to three Universities and had been a Visiting Professor to University of Lagos and Osun State University. 

Among his international travels, in May 2014, Professor Oloke was specially invited to All Saints University College of Medicine in St Vincent and Grenadines as a Foundation Dean for the Faculty of Science. During his stay in All Saints University he played a major role in the accreditation excise of the University and assisted the University in setting up a Research Committee.  

He has been the Chairman LAUTECH Christian Community since 1991 till date. He was the Ogbomoso Baptist Conference Representative at National Executive of Nigerian Baptist Convention for eight years. 

In August 2018 Professor J K Oloke was appointed as the Pioneer Vice Chancellor of Precious Cornerstone University Ibadan. He has been able to bring on board his wealth of experience to build a university with strong entrepreneurship drive empowering students to be employer of labor. The first set of students graduated in a Convocation Ceremony that was held in November 2022. 

At the advent of COVID-19, Professor Oloke led other scientists to develop two COVID-19 vaccines. The vaccines are at the stage of animal trials.

Professor Oloke is a Certified Health and Wellness Coach by the American College of Lifestyle Medicine. He is also a Certified Behavioral Coach by Precision Nutrition. 

He is married with children.